Sometime in the near future, paraplegic prison inmate Matt Mills meets The Board of Satoshi-Telefair Industries, who thank him for joining the Program. Under pressure and with a promise to make him walk again, Mills agrees to volunteer. He is injected with a synthetic nanomaterial and suffocated, only to wake up with restored use of his legs, yet alone in a steel cell in the first spoke of an experimental apparatus - The Wheel. A series of assailants inflict a multitude of damage to Mills body and torment his mind, yet the synthetic nanomaterial not only restores his damaged organs, it re-engineers his strength. The experiment might be designed to kill, but Mills is determined to survive - and get back to his daughter before The Board finds her first.
和徐克其他的片子比拟，《新龙食客栈》中的音乐不太风行，不像《男儿当自强》《沧海一声笑》传唱度那末高，这也是和影片的气概有关，这部片子中的配乐更多的是讲求功能性，而没有年夜段的旋律。
